Accelerating Innovations into CarE (AICE)

The Accelerating Innovations in CarE (AICE) program offers staged funding streams and support to Alberta’s small- and medium-sized enterprises (SMEs) that require robust scientific and clinical evidence to develop, advance and commercialize cutting edge new health technologies.

On This Page

Program Status: Active
Program Status refers to the state of work going on within this particular program. If the Program is 'Active', it is either accepting new applications or research is currently underway. If the Program is 'Inactive', the Program is neither accepting new applications nor is any research being conducted.
Intake Status: Open
Intake Status refers to the state of the Program's call for new applications. If the Intake is displaying 'Open', the Program is accepting new applications. If the Intake is displaying 'Closed', the Program is not accepting new applications.

Program at a Glance

Business Area: Health Innovation
Priority Area(s): AICE is a competition-based funding program that provides support to validate and advance product-market fit, business readiness, regulatory compliance, and technical development.
Program Guide: AICE - Program Guide

Eligibility

Alberta-based: Yes
Organization Type: Small to Medium Enterprise

Overview

The AICE program supports Alberta health technology ventures to grow and generate the evidence needed along their journey to achieve validation, market access, and start scaling. The objectives are to mitigate the risks faced by innovative Alberta health technology SMEs that require preclinical and clinical evidence to get to market by providing non-dilutive funding and access to advice and partners along the way.

AICE offers two funding streams, Validate, and Market Access, based-upon the proposed project activities and the stage of readiness of the technology, the product-market fit, the business, and regulatory compliance:

 

Each stage is outlined further with details of specific activities and milestones to be achieved for each domain in the Health Innovation Roadmap document. Click the graphic below to access the document:

The roadmap is a guide to assess your stage of readiness and alignment to the program streams. Applicants will work closely with Alberta Innovates to determine which funding stream is most appropriate during the application process.

Funding Available: up to 75% of total eligible Project Costs depending on stream:

Funding Stream:

AICE-Validate

AICE-Market Access

Funding limit from Alberta Innovates:

up to $300,000

up to $300,000-600,000*

What the funding stream supports:

Technology refinement and early validation of technology safety, efficacy and value proposition.

Later stage efficacy validation and post-market studies to achieve market access and adoption in various jurisdictions.

Stage required before applying:

Readiness level 4 in all domains completed

Readiness level 6 in all domains completed

*to apply for more than $300,000 under the AICE Market Access program stream see the Program Guide for details.

A minimum of 25 per cent of total eligible Project Costs must be provided by the Applicant as cash or in-kind contributions.

Term: Up to 24 months

The success of this program will be measured in aggregate across the portfolio of projects. While individual project outcomes are expected, all projects should align with the Program Objectives and contribute to the Indicators of Success outlined below:

Program Objectives:

Generate economic benefits to the province by commercializing Alberta- health technologies that will make a positive health impact, both locally and globally.

Outcomes
  • Increase the number of Alberta health technologies that commercially advance, achieve regulatory compliance, enter the market and are available to patients and care providers; and
  • Attract private investment, generate revenue growth, and create high quality jobs within Alberta’s health and life sciences industry.
Indicators of success
  • (%) projects progressing along client journey.
  • (#) products achieving regulatory approvals
  • ($) investment attraction.
  • ($) revenue generation.
  • (%) growth in employees.

Open Intakes

AICE - Intake

Due date: Continuous

More details

Eligibility

The AICE program is open to:

  • Alberta-based for-profit Small-medium sized Enterprises (SMEs) with an Alberta footprint, which is determined by the following:
    • Significant physical and corporate operational presence in Alberta.
    • Appropriate Alberta ownership.
    • Discernable intent that operational benefits will flow primarily within the province of Alberta;

with projects that include:

  • Innovative technologies with potential to directly improve health outcomes and require significant preclinical, safety or clinical efficacy evidence generation to ultimately achieve regulatory approval, reimbursement and/or market adoption

Generally NOT a good fit:

  • business management and operational clinic or hospital backend software, natural health products, and unregulated products, such as digital health information apps, virtual communication platforms, direct to consumer goods, wellness products, etc..

Consult the Program Guide for further eligibility criteria and our website for other programs you may be eligible for.

How To Apply

  1. Self Assess Fit– Review the Program Guide (posted above) and Support Resources below to confirm fit to all eligibility requirements and program objectives.
  2. Intake Form– Complete the “AICE Intake Form” via SmartSimple, our online application portal. Applicants are strongly encouraged to submit an Intake Form as early as possible, and no later than 6 weeks before a Full Application submission deadline.
  3. Intake Meeting– Wait for us to schedule an intake meeting with you to ensure program fit and provide support. Applicants who demonstrate appropriate readiness and meet basic eligibility requirements will be invited to apply.
  4. Full Application– Complete the Full Application via our online application portal. Full Applications are reviewed in multiple cohorts throughout the year. Upcoming application dates are noted below.

If you have any questions about the application process, feel free to contact Alberta Innovates at any time.

Application Deadlines

Applicants must submit Intake Forms at least 6 weeks in advance of the posted application deadline to be considered, and must submit their Full Applications by 4:00 pm Mountain time on the following submission dates:

  • July 18, 2025 (Intake deadline: June 6, 2025)
  • October 17, 2025 (Intake deadline September 5, 2025)
  • January 16, 2026 (Intake deadline December 5, 2026)

Evaluation Process

Applications are reviewed by Alberta Innovates employees and external expert reviewers. We evaluate submitted applications to the AICE program based on the technology, business opportunity, risk profile and potential size of the return to Alberta. Applicants who are declined may re-apply after a six-month cooling-off period.

Consult the Program Guide for full evaluation details.

Additional Alberta Innovates Supports and Resources

Health Tech Commercialization Supports – Alberta Innovates partners with a variety of other organizations in the ecosystem to provide support for Health Innovators.  View the Health Tech Commercialization Supports page here

Entrepreneurial Investments – Alberta Innovates offers a variety of related, high demand entrepreneurial investment programs that are of interest to SMEs. View the Entrepreneurial Investments page here.

Technology Development Advisors– provide front-line business coaching and technology development advice to small and medium-size enterprises in technology or knowledge-based industries. View the Technology Development Advisors page here.

Regional Innovation Networks– Entrepreneur-centric, community-based networks with the goal of providing programs and services to accelerate growth of technology and knowledge-based businesses in Alberta jurisdictions. View the Regional Innovation Networks page here.

Support Resources

Contact

Jose Raez

Senior Business Partner, Health Innovation


Open and Upcoming Intakes

AICE - Intake

The AICE program supports the advancement of innovative Alberta health ventures along their journey to generate the evidence needed to achieve proof of concept, validation and market access.

Funded Projects

View All Projects

AICE Market Access - Funded Projects

16 projects

Jan 1, 2020 – Jan 1, 2027

AICE Concepts - 2025 Recipients

September 2024 - February 2028

AICE Concepts - 2024 Recipients

February 2024 - January 2027

AICE Concepts - 2022 Recipients

8 projects

February 2022 to January 2025

AICE Concepts - 2023 Recipients

6 projects

February 2023 to January 2026

Discover More

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